Minimum bid jumped to $10

I've been running PPC for awhile for a set of keyword and all of a sudden, the minimum bid for everything is $10. 
Google has my Quality Score as poor, it was always at least OK prior.
I have Google Goggles and it has my Quality Score as Great.
I've tried to change the URL for the ad to other websites too, to see if it was my site only that was affected, but it seems to be across the board for that keyword, regardless of your site.

Any ideas?

If your clickthrough rate is really low google will slap you.

It's hard for me to give you any advice without seeing the site, keywords and ctr's.

We have found that at times google has a hard-on for some keywords and markets. It could very well be an editorial thing as well. Some markets are watched really close.

Bottom line is if you implement everything that google goggles tells you your quality score should be great. If it's not your overall account karma could be bad and that is something Goggles can't measure. Your domain, campaign or adgroup may have bad karma as well. These factors may contribute to a slap as well.

I'm thinking it must be the market being slapped in general because like I said, I've determined it's not my website because it's $10 for ANY site I run the ad for.  So that rules out domain, display url, and virtually all on page factors. 
I've also tried setting up a new campaign under a new account and the min bid was immediately 10 bucks as well, so it's not my CTR or Ad Group performance either.

[SOFTWARESAVER]

Hi Rich2 Yep it sounds like its the url and product domain.
They just don't like it.

If your going to be moving on from this one then it would be good (If you feel you can)
to let others on the forum know what it was.

At least it may help one or two people from getting the same Google Stick!

Keep Smiling :-)
Software Saver.

That's what I'm saying..it's NOT my url or domain because I've run the ad for multiple domains and it's $10 for all of them. 

What I did is opened up a brand new account so all my ad groups, past performance , and whatnot were out of the equation.

Then I created a new ad for the one keyword in question.

Then I tried it with about a dozen other sites (not mine) and no matter what site I picked the min bid was $10.

So instead of putting in MY site, I ran ads for other people's sites. Big sites that would be crazy relevant, like MayoClinic's page on the subject, competitors, goverment and edu sites, etc.

They were all $10.

Plus since every single competitor went bye bye overnight and not a single ad displays anymore for anyone, I don't think it's just me or related to my site.

I've never heard of a group of keywords getting slapped like that.

It's not gambling or anything like that either, it's a medical niche.

It's also not competitive enough that the bid price could just be that high, there were only about 3 or 4 bidders and I was always #1 for about 30 cents, plus like I said, nobody is displaying now.

So I *think* I've isolated enough variables to know it's not my site specifically and it's the keyword itself. Like someone at Google doesn't want ads showing for it at all.

Hopefully I'm making sense. Let me know if I'm on glue.

[SOFTWARESAVER]

Nope your not on glue but you sure are on the wrong keyword! 

Shame its gone like that...whats the situation on the other search engines?
Also whats the situation with site targeted stuff.
Have you thought about doing some site targeted stuff on the sites that come up in the natural search?
Would get you back in the game???

Site targeted is gone too, no impressions at all.

Other PPC like Yahoo is fine.

The good thing is that this wasn't hugely profitable for me anyway.  But it's scary because if it were another product that pays my mortgage I'd be hosed.